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By Robert B. Green (auth.)

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A base-sequence-dependent fluorescence lifetime was measured with a nitrogen laser pumped dye laser in quinacrine mustard-DNA complexes by Andreoni et al. 48, 49~. The excitation took place at 419 nm corresponding to the absorption peak of quinacrine mustard. A nonexponential decay for AT complexes and an exponential decay for GC complexes (x = 18 ns) was found (Fig. 11). Base-sequence-dependent energy transfer processes from DNA-bases to intercalated dye molecules in solution were measured by Anders 44, 51) using a frequency doubled pulsed dye laser (Fig.

Appl. Phys. 18, 333 (1979) 52. : Biopolymers 1,401 (1963) 53. Sloper, R. , Tuscott, I. , Land, E. : Photochem. Photobiol. 29, 1025 (1979) 54. Smith, K. : J. Invest. Dermat. 77, 2 (1981) 55. Shank, C. , Ippen, E. , Bersohn, R. : Science 193, 50 (1976) 56. Greene, B. , Hochstrasser, R. , Weisman, R. , Eaton, W. : Proc. Nat. Acad. Sci. USA 75, 5255 (1978) 57. Noe, L. , Eisert, W. , Rentzepis, P. : ibid. 75, 573 (1978) 58. Martin, J. : in ref. [9], pp. 223 59. Friedman, J. , Lyons, K. B. : in ref.

Ware, B. R. : in ref. [5], Vol. 2, pp. 199 25. , Rigler, R. : in Tunable Lasers and Applications (ed. ), Heidelberg: Springer 1976 26. Melamed, M. , Mullaney, P. F~, Mendelsohn, M. L. ): Flow Cytometry and Sorting, New York: Wiley 1979 27. Horan, P. , Wheeles, L. L. : Science 198, 149 (1977) 28. : Appl. Phys. 18, 177 (1979) 29. Campillo, A. , Shapiro, S. : in ref. [20], pp. 364 30. Parson, W. : in ref [5], Vol. I, pp. 339 31. , Alfano, R. R. : Biophys. J. 14, 269 (1974) 32. Kolman, V. H,, Shapiro, S.

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